Lets suppose you made some changes on your OS configuration that require the reload of the network services,
for example you made a change on your /etc/hosts file
This two basic commands are needed in order to reach the goal
First type:
sudo sh
Give the root password
And then type:
sudo ifconfig en0 down
and then to start it back up type
sudo ifconfig en0 up
This basically restarts your nic adapter which in essence will reload the basic network configration thus reading the changes
you made like in the /etc/hosts file.
Felipe